• Lead exposure in last century shrank IQ

    From ScienceDaily@1:317/3 to All on Mon Mar 7 21:30:50 2022
    Lead exposure in last century shrank IQ scores of half of Americans,
    study finds
    Leaded gasoline calculated to have stolen more than 800 million
    cumulative IQ points since the 1940s

    Date:
    March 7, 2022
    Source:
    Duke University
    Summary:
    Researchers calculate that exposure to car exhaust from leaded
    gas during childhood stole a collective 824 million IQ points
    from over 170 million Americans alive today, more than half of
    the population of the United States.



    FULL STORY ==========================================================================
    In 1923, lead was first added to gasoline to help keep car engines
    healthy.

    However, automotive health came at the great expense of our own health
    and well-being.


    ==========================================================================
    A new study calculates that exposure to car exhaust from leaded gas
    during childhood stole a collective 824 million IQ points from more
    than 170 million Americans alive today, about half the population of
    the United States.

    The findings, from Aaron Reuben, a PhD candidate in clinical psychology at
    Duke University, and colleagues at Florida State University, suggest that Americans born before 1996 may now be at greater risk for lead-related
    health problems, such as faster aging of the brain. Leaded gas for cars
    was banned in the U.S.

    in 1996, but the researchers say that anyone born before the end of that
    era, and especially those at the peak of its use in the 1960s and 1970s,
    had concerningly high lead exposures as children.

    The team's paper appeared the week of March 7 in the journal Proceedings
    of the National Academy of Sciences.

    Lead is neurotoxic and can erode brain cells after it enters the body. As
    such, there is no safe level of exposure at any point in life, health
    experts say.

    Young children are especially vulnerable to lead's ability to impair
    brain development and lower cognitive ability. Unfortunately, no matter
    what age, our brains are ill-equipped for keeping it at bay.

    "Lead is able to reach the bloodstream once it's inhaled as dust, or
    ingested, or consumed in water," Reuben said. "In the bloodstream, it's
    able to pass into the brain through the blood-brain barrier, which is
    quite good at keeping a lot of toxicants and pathogens out of the brain,
    but not all of them." One major way lead used to invade bloodstreams
    was through automotive exhaust.



    ==========================================================================
    To answer the complex question of how leaded gas use for more than
    70 years may have left a permanent mark on human health, Reuben and
    his co-authors Michael McFarland and Mathew Hauer, both professors of
    sociology at Florida State University, opted for a fairly simple strategy.

    Using publicly available data on U.S. childhood blood-lead levels,
    leaded-gas use, and population statistics, they determined the likely
    lifelong burden of lead exposure carried by every American alive in
    2015. From this data, they estimated lead's assault on our intelligence
    by calculating IQ points lost from leaded gas exposure as a proxy for
    its harmful impact on public health.

    The researchers were stunned by the results.

    "I frankly was shocked," McFarland said. "And when I look at the numbers,
    I'm still shocked even though I'm prepared for it." As of 2015, more
    than 170 million Americans (more than half of the U.S.

    population) had clinically concerning levels of lead in their blood when
    they were children, likely resulting in lower IQs and putting them at
    higher risk for other long-term health impairments, such as reduced brain
    size, greater likelihood of mental illness, and increased cardiovascular disease in adulthood.



    ========================================================================== Leaded gasoline consumption rose rapidly in the early 1960s and peaked in
    the 1970s. As a result, Reuben and his colleagues found that essentially everyone born during those two decades are all but guaranteed to have
    been exposed to pernicious levels of lead from car exhaust.

    Even more startling was lead's toll on intelligence: childhood lead
    exposure may have blunted America's cumulative IQ score by an estimated
    824 million points -- nearly three points per person on average. The researchers calculated that at its worst, people born in the mid-to-late
    1960s may have lost up to six IQ points, and children registering the
    highest levels of lead in their blood, eight times the current minimum
    level to initiate clinical concern, fared even worse, potentially losing
    more than seven IQ points on average.

    Dropping a few IQ points may seem negligible, but the authors note
    that these changes are dramatic enough to potentially shift people
    with below-average cognitive ability (IQ score less than 85) to being classified as having an intellectual disability (IQ score below 70).

    Moving forward, McFarland is analyzing the racial disparities of childhood
    lead exposure, hoping to highlight the health inequities suffered by Black children, who were exposed more often to lead and in greater quantities
    than white children.

    Reuben's next step will be to examine the long-term consequences of past
    lead exposure on brain health in old age, based on previous findings
    that adults with high childhood lead exposure may experience accelerated
    brain aging.

    "Millions of us are walking around with a history of lead exposure,"
    Reuben said. "It's not like you got into a car accident and had a
    rotator cuff tear that heals and then you're fine. It appears to be an
    insult carried in the body in different ways that we're still trying to understand but that can have implications for life."

    ========================================================================== Story Source: Materials provided by Duke_University. Original written
    by Dan Vahaba. Note: Content may be edited for style and length.


    ========================================================================== Journal Reference:
    1. Michael J. McFarland, Matt E. Hauer, Aaron Reuben. Half of US
    population
    exposed to adverse lead levels in early childhood. Proceedings
    of the National Academy of Sciences, 2022; 119 (11) DOI:
    10.1073/pnas.2118631119 ==========================================================================

    Link to news story: https://www.sciencedaily.com/releases/2022/03/220307162011.htm

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